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:: year 8, Issue 1 (Journal of Acoustical Engineering Society of Iran 2020) ::
مجله علمی پژوهشی انجمن مهندسی صوتیات ایران 2020, 8(1): 1-6 Back to browse issues page
Effect of 3 MHz ultrasound radiation on retinoblastoma cell line (Research Article)
S. Moradi, M. Mokhtari Dizaji , F. Ghassemi, S. Sheibani, F. Asadi Amoli
Abstract:   (765 Views)
Ultrasound hyperthermia is a new way to treat cancerous tumors. Retinoblastoma is one of the most common malignant ocular tumors in children. Since hyperthermia is an effective treatment for cancer cells, the effect of hyperthermia on retinoblastoma cells was investigated in this study. The purpose of this study was to determine the effect of duration of 3 MHz ultrasound hyperthermia on Y79 cell death after 48 hours using MTT assay. In this study, the percentage of cell viability after 48 hours in treatment groups with a duration of hyperthermia more than 4 minutes was significantly different from the control group and in the treatment group with hyperthermia time of 9 minutes and 11 minutes, 50% and 69% of cells were killed, respectively. Therefore, it can be concluded that ultrasound hyperthermia may be a promising therapeutic option.
 
Keywords: Ultrasound waves, Retinoblastoma cell, Y79, Hyperthermia, MTT test, Cell death.
Full-Text [PDF 115 kb]   (249 Downloads)    
Type of Study: Research | Subject: Bioacoustics
Received: 2020/02/26 | Accepted: 2020/03/25 | Published: 2020/09/10
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Moradi S, Mokhtari Dizaji M, Ghassemi F, Sheibani S, Asadi Amoli F. Effect of 3 MHz ultrasound radiation on retinoblastoma cell line (Research Article). مجله علمی پژوهشی انجمن مهندسی صوتیات ایران. 2020; 8 (1) :1-6
URL: http://joasi.ir/article-1-174-en.html


year 8, Issue 1 (Journal of Acoustical Engineering Society of Iran 2020) Back to browse issues page
مجله علمی-پژوهشی انجمن lمهندسی صوتیات ایران Journal of Acoustical Engineering Society of Iran
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