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In this study, the cavitation activity induced by the ultrasound irradiation on exposure parameters has been measured by subharmonic analysis. Experiments were performed in a 1 MHz field. The effect of duty cycles changes with 2.2 W/cm2 intensity and acoustic intensity changes in continuous mode on subharmonic intensity were measured. The correlation between fluorescence intensity of terephthalic acid chemical dosimetry and subharmonic intensity analysis were analyzed by Pearson correlation (p<0.05). It has been shown that the subharmonic intensity for continuous mode is higher than that for pulsing mode (p<0.05). The subharmonic intensity (µW/cm2) significantly correlates with the fluorescence intensity (Count). The fluorescence intensity due to chemical dosimetry could be estimated by subharmonic intensity due to subharmonic spectrum analysis. It is concluded that subharmonic spectrum analysis is an appropriate method to examine the acoustic cavitation activity.

Keywords: Acoustic cavitation, Subharmonic analysis, Terephthalic acid dosimetry, Coefficient of correlation.

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